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Asthma Control Questionnaire in children: validation, measurement properties, interpretation.
E F Juniper1, K Gruffydd-Jones, S Ward
1Dept of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada. juniper@qoltech.co.uk
The Asthma Control Questionnaire (ACQ) is valid and reliable for assessing asthma control in children aged 6-16 years. This tool effectively measures symptom reduction and improves asthma management in pediatric patients.
Area of Science:
- Pediatric Pulmonology
- Clinical Assessment Tools
- Asthma Management
Background:
- The Asthma Control Questionnaire (ACQ) is validated for adults.
- Pediatric asthma management requires reliable assessment tools.
- Current tools may not fully capture pediatric asthma control.
Purpose of the Study:
- To evaluate the validity, measurement properties, and interpretability of the ACQ in children aged 6-16 years.
- To establish the ACQ's reliability and responsiveness to changes in asthma control.
- To determine the Minimal Important Difference (MID) for the ACQ in pediatric populations.
Main Methods:
- 35 children (6-16 years) completed ACQ, Mini-PAQLQ, RCP 'Three Questions' at 0, 1, and 4 weeks.
- Parents completed P-AQLQ; children used Asthma Control Diary and PEF measurements.
- Clinicians and parents used Global Rating of Change Questionnaires; test-retest reliability assessed in 19 stable children.
Main Results:
- ACQ demonstrated good test-retest reliability (ICC 0.79) in stable children.
- ACQ was responsive to changes in asthma control (p=0.026) with a mean MID of 0.52 ± 0.45.
- Correlations between ACQ and other outcomes supported its validity for measuring pediatric asthma control.
Conclusions:
- The Asthma Control Questionnaire (ACQ) exhibits strong measurement properties and is valid for children aged 6-16 years.
- The ACQ is a reliable and responsive tool for assessing pediatric asthma control.
- Trained interviewers are recommended for ACQ administration in children aged 6-10 years.
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