Related Experiment Videos
[Chronotherapy of tenoxicam]
A Reinberg1, R Manfredi, M F Kahn
1Fondation A. de Rothschild, CNRS, URA 581, Paris.
Therapie
|March 1, 1991
Abstract:
A study was carried out in order to investigate the chronotherapy (dosing time dependency) of an NSAID, the tenoxicam administered in ankylosing spondylitis, rheumatoid arthritis and osteoarthritis of the hip. These variations in efficacy exist as much for pain as for stiffness and maximum efficacy is obtained with administration at 8 am or 12 pm. Since the tolerance was good, we recommend midday as an optimal once-a-day dosing time.