[The questionnaire "Profile of the subjective quality of life". First data of validation]

The questionnaire "Profile of the Subjective Quality of Life" (in french, PQVS) is devoted to the assessment of quality of life in therapeutic trials. On a sample of 588 subjects, factorial analysis confirm that it is not restricted to the assessment of the health, as most of the instruments actually available for that purpose. Its internal consistency is high. Correlations clearly show that its specific questions assessing the degrees of a) satisfaction and b) involvement (concerning each item) are clearly understood as having different meanings. Multiple regressions demonstrate that these specific questions strongly contribute to the explanation of the global quality of life or of the satisfaction concerning each item. Its reliability is good. It is very well accepted, and completed in no more than 15 to 30 minutes. This questionnaire is thus matching the criteria defining an effective assessment of the quality of life.