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[Drug interactions of cyclosporine. Literature review]
S Bouquet1, G Chapelle, M C Perault
1Laboratoire de Pharmacocinétique, CHRU la Milétrie, Poitiers.
Therapie
|March 1, 1991
Abstract:
The cyclosporine is widely used as an immuno-suppressive agent in association with others drugs. Its narrow therapeutic range requires frequent monitoring. We suggest a literature review of suspected or confirmed drug interactions. The classification is presented as: absorption interactions; pharmacokinetic interactions in antiinfectious, anticonvulsants, cardiovascular drugs, H2 antagonists agents, hormonotherapy; pharmacodynamic interactions associated to increased cyclosporine nephrotoxicity.