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Corneal Sensitivity Testing Procedure for Ophthalmologic and Optometric Patients
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Central toxic keratopathy.

Majid Moshirfar1, Ribhi Hazin, Yousuf M Khalifa

  • 1Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah Medical Center Salt Lake City, UT 84132, USA. majid.moshirfar@hsc.utah.edu

Current Opinion in Ophthalmology
|June 10, 2010
PubMed
Summary
This summary is machine-generated.

Central toxic keratopathy syndrome (CTK) is a rare, noninflammatory postsurgical condition causing corneal opacity and hyperopic shift. Recent evidence advises against steroid use, recommending conservative management for spontaneous resolution.

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Area of Science:

  • Ophthalmology
  • Corneal Diseases

Background:

  • Central toxic keratopathy syndrome (CTK) is a rare, self-limited, noninflammatory postsurgical condition.
  • It presents with central corneal opacity and a significant hyperopic shift.
  • CTK is often misdiagnosed due to its resemblance to other serious conditions.

Purpose of the Study:

  • To review recent literature on central toxic keratopathy syndrome (CTK).
  • To clarify the management of CTK based on current evidence.

Main Methods:

  • Literature review of recent studies on CTK.
  • Analysis of clinical presentation, diagnosis, and treatment outcomes.

Main Results:

  • CTK is characterized by central corneal opacity and hyperopic shift.
  • Despite being noninflammatory, CTK is sometimes treated with steroids due to overlapping symptoms.
  • Recent studies discourage steroid use in CTK.

Conclusions:

  • Steroid administration is contraindicated in CTK.
  • Steroids may exacerbate refractive alterations in patients with CTK.
  • Conservative management allowing spontaneous resolution is recommended.