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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Stress Prevention and Stress Management Techniques IV01:26

Stress Prevention and Stress Management Techniques IV

Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Chronic Obstructive Pulmonary Disease II: Emphysema01:23

Chronic Obstructive Pulmonary Disease II: Emphysema

Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation

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Updated: Jun 12, 2026

Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System
06:07

Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System

Published on: October 22, 2020

Smoking and skin disease.

S F Thomsen1, L T Sørensen

  • 1Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark.

Skin Therapy Letter
|June 10, 2010
PubMed
Summary

Tobacco smoking significantly impacts skin health, worsening conditions like psoriasis and skin cancer while potentially protecting against others. Smoking-induced oxidative stress underlies these complex dermatologic effects.

Area of Science:

  • Dermatology
  • Public Health
  • Toxicology

Background:

  • Tobacco smoking is a major preventable health risk.
  • Its role in skin disease etiology is not well understood.
  • Evidence suggests smoking influences numerous dermatologic conditions.

Purpose of the Study:

  • To review the current evidence on the role of tobacco smoking in the development and exacerbation of skin diseases.
  • To explore the potential protective effects of smoking in certain dermatologic conditions.
  • To elucidate the pathophysiologic mechanisms linking smoking to skin disease.

Main Methods:

  • Literature review of epidemiological studies and case reports.
  • Analysis of findings linking smoking to specific skin diseases.

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Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations

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  • Examination of proposed mechanisms of action, including oxidative stress.

    • Main Results:

    • Smoking is implicated in systemic lupus erythematosus, psoriasis, cutaneous squamous cell carcinoma, and genital warts.
    • Smoking may offer protective effects in pemphigus vulgaris, pyoderma gangrenosum, and Behçet's disease.
    • Degenerative conditions like skin wrinkling and impaired wound healing are associated with smoking.

    Conclusions:

    • Tobacco smoking has a complex and multifaceted role in skin disease.
    • Mechanisms likely involve smoking-induced oxidative stress affecting inflammatory cells and extracellular matrix.
    • Further research is needed to fully understand these relationships and inform public health strategies.