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Caroli's syndrome with ureterovesical calculi in a young child

Yashwant K Rao1, Tanu Midha

  • 1Department of Pediatrics, GSVM Medical College, Kanpur, India.

Indian Journal of Pediatrics
|June 10, 2010
PubMed

Insights

A pediatric case presents with fever, abdominal pain, and hepatomegaly, revealing complex urinary tract and biliary system issues. The findings highlight significant kidney and liver complications in an infant, emphasizing the need for comprehensive diagnostics.

Area of Science:

  • Pediatric Nephrology
  • Hepatology
  • Medical Imaging

Background:

  • A rare case of a pediatric patient presenting with severe abdominal symptoms.
  • Investigating the co-occurrence of biliary and renal pathologies in infants.

Observation:

  • An 18-month-old boy exhibited fever, abdominal pain, and hepatomegaly.
  • Computed Tomography (CT) scan demonstrated intrahepatic biliary dilatation with a central dot sign and bilateral nephrocalcinosis.
  • The patient also had ureteric and urinary bladder stones, with right-sided obstructive hydroureteronephrosis caused by a 1.5 cm ureterovesical calculus.

Findings:

  • Liver biopsy indicated early hepatic fibrosis.
  • The combination of biliary dilatation, nephrocalcinosis, and urinary calculi suggests a complex systemic condition.

Implications:

  • This case underscores the importance of considering multi-system involvement in pediatric presentations of abdominal pain and fever.
  • Early diagnosis and management of such complex conditions are crucial for preventing progressive organ damage.
  • Further research into the underlying etiology connecting biliary and renal stone formation in children is warranted.

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