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Related Concept Videos

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Cholecystitis01:20

Cholecystitis

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Cirrhosis I: Introduction01:23

Cirrhosis I: Introduction

Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
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Cirrhosis II: Pathophysiology01:24

Cirrhosis II: Pathophysiology

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Related Experiment Video

Updated: Jun 12, 2026

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
08:56

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis

Published on: February 10, 2015

Sclerosing cholangitis-like changes in hepatobiliary tuberculosis.

Yasemin Ozin1, Erkan Parlak, Zeki Mesut Yalin Kiliç

  • 1Department of Gastroenterology, Türkiye Yüksek Ihtisas Training and Research Hospital, Ankara, Turkey. yoozderin@gmail.com

The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology
|June 10, 2010
PubMed
Summary

Primary hepatobiliary tuberculosis is rare and mimics sclerosing cholangitis. Diagnosis requires high suspicion, especially in developing nations, for accurate tuberculosis management.

Related Experiment Videos

Last Updated: Jun 12, 2026

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
08:56

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis

Published on: February 10, 2015

Area of Science:

  • Hepatology
  • Infectious Diseases
  • Gastroenterology

Background:

  • Atypical presentations of tuberculosis (TB) pose diagnostic challenges, particularly in resource-limited settings.
  • Primary hepatobiliary tuberculosis is an uncommon manifestation requiring a high index of suspicion for timely diagnosis.

Observation:

  • A case presented with obstructive jaundice, intrahepatic bile duct dilation, and porta hepatis lymphadenopathy.
  • Endoscopic retrograde cholangiopancreaticography revealed bile duct irregularities mimicking sclerosing cholangitis.
  • Liver and cervical lymph node biopsies confirmed tuberculosis with characteristic granulomas and acid-fast bacilli.

Findings:

  • The patient's presentation and imaging findings closely resembled primary sclerosing cholangitis.
  • Histopathological examination of liver and lymph node biopsies provided definitive evidence of tuberculosis.

Implications:

  • Primary hepatobiliary tuberculosis can mimic primary sclerosing cholangitis, necessitating its inclusion in the differential diagnosis.
  • This case highlights the importance of considering tuberculosis in patients with unexplained sclerosing cholangitis-like biliary changes.