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Related Experiment Video

Updated: Jun 12, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
05:46

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

Ocular aberrations after wavefront optimized LASIK for myopia.

Prema Padmanabhan1, Subam S Basuthkar, Roy Joseph

  • 1Medical Research Foundation, Sankara Nethralaya, 18 College Road, Chennai, Tamil Nadu, India.

Indian Journal of Ophthalmology
|June 11, 2010
PubMed
Summary
This summary is machine-generated.

Wavefront Optimized (WFO) Laser-Assisted In Situ Keratomileusis (LASIK) effectively corrects myopia, but it significantly increases higher-order aberrations. Larger ablation zones can help reduce induced spherical aberration, improving visual outcomes.

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Published on: September 16, 2025

Area of Science:

  • Ophthalmology
  • Refractive Surgery
  • Optometry

Background:

  • Myopia correction is a common refractive surgery procedure.
  • Wavefront-guided and wavefront-optimized (WFO) LASIK aim to improve visual quality.
  • Understanding induced aberrations is crucial for refractive surgery outcomes.

Purpose of the Study:

  • To evaluate changes in ocular aberrations following WFO LASIK for myopia correction.
  • To identify factors influencing these aberration changes.

Main Methods:

  • Prospective case series involving 59 patients (117 eyes).
  • WFO LASIK performed using Hansatome microkeratome and Allegretto laser.
  • Ocular aberrations measured preoperatively and at 1 and 6 months postoperatively using Allegretto wave analyzer.

Main Results:

  • Excellent visual acuity achieved in 87% (20/20 or better) and refractive correction within +/-0.5D in 89% of eyes.
  • A 1.96-fold increase in total higher-order aberrations was observed.
  • Induced aberrations showed correlation with attempted refractive correction; larger ablation zones reduced spherical aberration.

Conclusions:

  • WFO LASIK provides excellent visual outcomes for myopia correction.
  • Significant induction of higher-order aberrations occurs post-WFO LASIK.
  • Larger ablation zones are associated with reduced induction of spherical aberration.