Compulsive singing associated with a dopamine agonist in Parkinson disease

To describe a patient with Parkinson disease in whom compulsive singing developed without other types of pathologic behavior after starting treatment with pergolide.

An 82-year-old woman with Parkinson disease was given pergolide (250 microg/d), without modifying the doses of other medications.

She started to hum the same melody and often sang songs repeatedly. Pergolide was discontinued, and the episodes of repetitive humming and singing were markedly decreased.

Our observations suggest that a dopamine agonist may contribute to compulsive singing in Parkinson disease.