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Updated: Jun 12, 2026

Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood
Published on: October 12, 2012
An evaluation of near-patient testing of anticoagulant control in general practice
Amanda Edgeworth1, Edward C Coles
1Vauxhall Practice, Chepstow, UK. edgeworth@doctors.org.uk
Purpose:
This paper aims to compare anticoagulant management in secondary care for the year prior to the introduction of near-patient testing in a general practice, and in the subsequent year after it was introduced.
Design/Methodology/Approach:
This paper is a retrospective, paired before-after study. Details of test results in the two-year-long periods on the 46 patients who met the inclusion criteria were collected and analysed pairwise.
Findings:
Despite an increase in the frequency of testing this set of patients were controlled as well in general practice as they had been with a secondary-care service, and better that in a number of studies in the literature.
Research Limitations/Implications:
This research reviews a recently introduced service at a single centre. Further research of patient satisfaction and adverse events in a multi-centre longer-term trial are desirable.
Practical Implications:
Technology now allows the increasing amount of individuals on anticoagualtion to be controlled with near-patient testing in general practice. This study shows that satisfactory control can be maintained in patients who transfer from a secondary care-based to a primary care-based service.
Originality/Value:
This paper demonstrates that a single general practice can provide a high quality anticoagulant service using near-patient testing and computer-based decision support. This adds to the already available evidence and will hopefully encourage other practices to adopt the same.
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