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Updated: Jun 12, 2026
07:53
Multidimensional Coculture System to Model Lung Squamous Carcinoma Progression
Published on: March 17, 2020
[Combined-modality therapy for lung cancer]
Satoru Miura1, Nobuyuki Yamamoto
1Division of Thoracic Oncology, Shizuoka Cancer Center.
Nihon Rinsho. Japanese Journal of Clinical Medicine
|June 12, 2010
Summary
Early and locally-advanced lung cancer can be cured with combined-modality therapy. This review covers standard and novel treatment strategies for non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC).
Area of Science:
- Oncology
- Pulmonology
- Medical Therapeutics
Context:
- Lung cancer treatment varies by histology and stage.
- Advanced lung cancer is generally incurable, but early and locally-advanced stages offer curative potential.
- Current standards involve surgery, radiotherapy, and chemotherapy, often in combined-modality approaches.
Purpose:
- To review established and emerging combined-modality treatment strategies for early and locally-advanced lung cancer.
- To highlight the integration of new molecular targeted drugs into treatment paradigms.
- To provide an overview of therapeutic options for non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC).
Summary:
- Combined-modality therapy, including surgery plus adjuvant chemotherapy, is standard for resectable non-small cell lung cancer (NSCLC) and stage I small cell lung cancer (SCLC).
- Chemoradiotherapy is the standard for unresectable locally-advanced NSCLC and limited-stage SCLC.
- Recent advancements include the availability and clinical trials of novel molecular targeted drugs.
Impact:
- This review informs clinicians about current and future treatment options for curable lung cancer stages.
- It emphasizes the importance of combined-modality therapy and emerging targeted therapies.
- Facilitates evidence-based decision-making for optimizing lung cancer patient outcomes.
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