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Anaphylaxis in Israel: experience with 92 hospitalized children

V Hoffer1, O Scheuerman, N Marcus

  • 1Department of Pediatrics B, Schneider Children's Medical Center of Israel, Petah Tikvah, Israel.

Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology
|June 12, 2010
PubMed

Insights

Anaphylaxis in children is often triggered by foods like milk and nuts, or by medications. Improved patient education on using epinephrine auto-injectors is crucial for managing recurrent allergic reactions.

Area of Science:

  • Pediatrics
  • Allergy and Immunology
  • Clinical Medicine

Background:

  • Limited data exists on pediatric anaphylaxis outside North America and Europe.
  • Understanding regional variations in anaphylaxis triggers and management is essential.

Purpose of the Study:

  • To investigate the characteristics of childhood anaphylaxis in Israel.
  • To identify common causes, clinical presentations, and treatment outcomes.

Main Methods:

  • Retrospective analysis of 92 pediatric anaphylaxis cases hospitalized over 12 years.
  • Data collected on demographics, triggers, co-morbidities, and treatments.

Main Results:

  • Foods (43%), medications (22%), and hymenoptera venom (11%) were primary triggers.
  • Anaphylaxis occurred mainly at home (56%); 52% had a history of atopy.
  • Epinephrine auto-injector use was low among patients with recurrent episodes, highlighting an educational gap.

Conclusions:

  • Food allergens are a significant cause of pediatric anaphylaxis in Israel.
  • Effective management requires addressing co-morbidities like atopy and improving emergency preparedness, including EpiPen utilization.

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