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Updated: Jun 12, 2026

Use of Primary Cultured Hippocampal Neurons to Study the Assembly of Axon Initial Segments
Published on: February 12, 2021
Matthew S Grubb1, Juan Burrone
1MRC Centre for Developmental Neurobiology, King's College London, 4th Floor, New Hunt's House, Guy's Campus, London SE1 1UL, UK. matthew.grubb@kcl.ac.uk
The axon initial segment (AIS) initiates action potentials and controls neuronal identity. Recent studies reveal its distinct domains, role as a transport barrier, and plasticity in response to neuronal activity.
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2026-06-19T13:36:26.427667+00:00