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Updated: Jun 12, 2026
11:51
Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making
Published on: March 2, 2011
[Evaluation of testosterone levels through distinct analytic methods in healthy men]
Concepción Sanabria Pérez1, José Angel Díaz Pérez
1Servicio de Endocrinología y Nutrición, Hospital Clínico San Carlos, Madrid, España.
Summary
Establishing normal testosterone ranges in young men is crucial for diagnosing hypogonadism. This study highlights the need for laboratories to define their own testosterone reference ranges based on the specific analytical methods employed.
Area of Science:
- Endocrinology
- Andrology
- Clinical Chemistry
Context:
- Plasma testosterone concentrations are vital for diagnosing hypogonadism.
- Establishing normal ranges is challenging due to age-related changes and analytical method variability.
Purpose:
- To determine normal testosterone ranges in healthy young men.
- To compare results from different testosterone measurement methods.
Summary:
- Total testosterone (TT), free testosterone (FT), calculated free testosterone (FTc), and bioavailable testosterone (BT) were measured in 20 healthy men (mean age 24.5 years).
- Significant correlations were found between FT and FTc, and FTc and BT.
- An inverse correlation existed between body mass index (BMI) and TT concentrations.
Impact:
- Results emphasize that normal testosterone ranges must be laboratory-specific, depending on the analytical method used.
- This finding is critical for accurate diagnosis and management of hypogonadism in young men.
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