Related Experiment Video
Updated: Jun 12, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Femoral artery complications associated with the Mynx closure device
1Interventional Neuroradiology Section, Dotter Interventional Institute, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239-3098, USA.
Insights
The Mynx vascular closure device, used after femoral artery procedures, was associated with a high rate of intravascular sealant and pseudoaneurysms in this small study. Further research is needed to assess long-term safety and efficacy.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Cardiology
Background:
- Vascular closure devices (VCDs) are commonly used after femoral artery catheterization to achieve hemostasis and facilitate patient ambulation.
- The Mynx vascular closure device utilizes an intravascular sealant to occlude the arteriotomy site.
Purpose of the Study:
- To evaluate the incidence of intravascular Mynx sealant and pseudoaneurysms following femoral artery closure.
- To assess the safety and potential complications associated with the Mynx device.
Main Methods:
- Retrospective review of patients undergoing femoral artery closure with the Mynx device.
- Analysis of follow-up vascular imaging (angiography) in a subset of patients who received the Mynx device.
- Assessment of 146 Mynx device deployments in 135 patients, with 27 follow-up studies.
Main Results:
- Intravascular Mynx sealant was identified in 18% (5/27) of follow-up vascular studies.
- Pseudoaneurysms were detected in 11% (3/27) of follow-up vascular studies.
- The study highlights potential complications associated with the Mynx device.
Conclusions:
- Femoral arterial closure with the Mynx vascular closure device was associated with a frequent occurrence of intravascular sealant and pseudoaneurysms in this cohort.
- These findings suggest a need for careful monitoring and further investigation into the long-term implications of Mynx device use.
Background And Purpose:
Devices to close a femoral arteriotomy are frequently used after catheterization for interventional radiology and cardiac procedures to decrease the time to hemostasis and ambulation and, potentially, to decrease local complications. The Mynx vascular closure device uses a sealant designed to occlude the access tract, resulting in hemostasis.
Materials And Methods:
We retrospectively reviewed all cases in which the Mynx device was used and for which follow-up angiography was available. A total of 146 devices were deployed in 135 patients. A follow-up vascular study visualizing the femoral artery was performed in 26 patients (27 studies).
Results:
There were 5 (5/27, 18%) cases of intravascular Mynx sealant on follow-up vascular imaging. Three pseudoaneurysms (3/27, 11%) were identified.
Conclusions:
In this small study, intravascular sealant and pseudoaneurysms were found frequently after femoral arterial closure with the Mynx vascular closure device.
Related Concept Videos
Aneurysm III: Interprofessional Care
Peripheral Artery Disease V: Postoperative Nursing Management
Aneurysm IV: Nursing Management
Cardiac Catheterization IV: Nursing Management
Cardiac Catheterization I: Pre-Procedure Overview
Aneurysm II: Clinical Manifestations and Diagnostic Studies

