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Concise approach to pupukeanane skeleton: synthetic study of chloropupukeananin
Takahiro Suzuki1, Susumu Kobayashi
1Faculty of Pharmaceutical Sciences, Tokyo University of Science (RIKADAI), 2641 Yamazaki, Noda-shi, Chiba 278-8510, Japan.
Organic Letters
|June 15, 2010
Abstract:
A concise synthesis of a highly functionalized chloropupukeananin (1) skeleton via a reverse electron-demand Diels-Alder reaction and intramolecular carbonyl-ene reaction sequence based on our proposed biosynthetic pathway is described.
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