[First trimester screening for Down syndrome: five years prospective experience]
A-S Weingertner1, N-T Trieu, M Kohler
1Pôle de gynécologie obstétrique, département d'échographie et de diagnostic anténatal, centre médicochirurgical et obstétrical SIHCUS, 19, rue Louis-Pasteur, 67303 Schiltigheim cedex, France. Anne-Sophie.Weingertner@sihcus.fr
Abstract:
First trimester screening for Down syndrome is yet to become the first intention strategy in France. This screening program at 11-14 weeks of gestation using maternal age, fetal nuchal translucency, maternal serum free beta-human chorionic gonadotropin and pregnancy-associated plasma protein-A has already been validated for a long time by many international studies. It seems to improve detection rate and decrease false positive rates. We report here five years prospective experience.
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