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The recycling endosome, also known as the endosomal recycling compartment (ERC), is a part of the slow-recycling process of the endocytic pathway. Molecules internalized through receptor-mediated endocytosis are either degraded in the lysosomes or are recycled to the plasma membrane through the fast- or slow-recycling route.
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Related Experiment Video

Updated: Jun 12, 2026

Scalable Step-by-Step Approach of Sustainable Bioplastic Production from Food Waste
08:14

Scalable Step-by-Step Approach of Sustainable Bioplastic Production from Food Waste

Published on: July 18, 2025

Waste and yet want not.

Daniel M Stoebel1, Daniel E Dykhuizen

  • 1Department of Biology and Biochemistry, The University of Houston, Houston, TX 77044, USA.

Molecular Cell
|June 15, 2010
PubMed
Summary

Wasteful protein expression in Escherichia coli (E. coli) is costly during the transition to exponential growth. This occurs due to a limited supply of ribosomes during this critical growth phase.

Area of Science:

  • Microbiology
  • Molecular Biology
  • Bacterial Physiology

Background:

  • Bacterial growth phases are critical for understanding cellular processes.
  • Protein expression is tightly regulated in response to environmental changes.
  • Escherichia coli (E. coli) is a model organism for studying bacterial physiology.

Discussion:

  • Shachrai et al. (2010) investigated the energetic costs of protein synthesis in E. coli.
  • The study identifies a specific growth phase where wasteful protein expression incurs a significant cost.
  • This cost is linked to the transition from stationary phase to balanced exponential growth.

Key Insights:

  • Wasteful protein expression is particularly detrimental during the shift from stationary to exponential growth.

Related Experiment Videos

Last Updated: Jun 12, 2026

Scalable Step-by-Step Approach of Sustainable Bioplastic Production from Food Waste
08:14

Scalable Step-by-Step Approach of Sustainable Bioplastic Production from Food Waste

Published on: July 18, 2025

  • A shortage of ribosomes is identified as the likely cause of this increased cost.
  • Understanding ribosome availability is crucial for optimizing protein production in E. coli.
  • Outlook:

    • Further research could explore strategies to mitigate the cost of protein expression during growth phase transitions.
    • This finding has implications for metabolic engineering and biotechnology applications involving E. coli.
    • Investigating ribosome dynamics in other bacterial species may reveal conserved mechanisms.