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Recycling Endosomes and Transcytosis

The recycling endosome, also known as the endosomal recycling compartment (ERC), is a part of the slow-recycling process of the endocytic pathway. Molecules internalized through receptor-mediated endocytosis are either degraded in the lysosomes or are recycled to the plasma membrane through the fast- or slow-recycling route.
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Cell Squeezing as a Robust, Microfluidic Intracellular Delivery Platform
08:02

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Published on: November 7, 2013

Hijacking cellular garbage cans.

Sonja Welsch1, Jacomine Krijnse Locker

  • 1European Molecular Biology Laboratory, Structural and Computational Biology Unit, 69117 Heidelberg, Germany.

Cell Host & Microbe
|June 15, 2010
PubMed
Summary
This summary is machine-generated.

Coronaviruses hijack cellular protein quality control pathways for viral genome replication. This study reveals how these viruses exploit host cell machinery to ensure their own propagation.

Area of Science:

  • Virology
  • Cell Biology
  • Molecular Biology

Background:

  • Viruses are obligate intracellular parasites that manipulate host cell processes.
  • Cellular quality control pathways are essential for maintaining protein homeostasis and degrading misfolded proteins.

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