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Related Experiment Videos

Postmortem viability of the human immunodeficiency virus.

K Püschel1, F Mohsenian, R Laufs

  • 1Institute of Forensic Medicine, University of Hamburg, Federal Republic of Germany.

International Journal of Legal Medicine
|March 1, 1991
PubMed
Summary

In 1989, approximately 0.5% of 2581 deceased individuals screened in Hamburg tested positive for Human Immunodeficiency Virus type 1 (HIV-1) antibodies. Viable HIV was detected in some blood samples up to 36 hours post-mortem.

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Area of Science:

  • Forensic Medicine
  • Virology
  • Public Health

Background:

  • The prevalence of Human Immunodeficiency Virus type 1 (HIV-1) in deceased populations requires ongoing surveillance.
  • Understanding post-mortem HIV viability is crucial for forensic investigations and occupational safety.

Purpose of the Study:

  • To determine the prevalence of HIV-1 antibodies in fatalities investigated at the Institute of Forensic Medicine in Hamburg in 1989.
  • To assess the viability of HIV in post-mortem blood samples under specific storage conditions.

Main Methods:

  • Screening of blood samples from 2581 fatalities for HIV-1 antibodies using serological tests.
  • Blood cultures were performed on cadaver samples to detect viable HIV.
  • Samples were analyzed from individuals stored under non-refrigerated conditions for up to 36 hours post-mortem.

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Main Results:

  • A prevalence rate of approximately 0.5% for HIV-1 antibodies was identified among the 2581 fatalities.
  • Thirteen cases were confirmed positive for HIV-1 antibodies.
  • Viable HIV was successfully isolated from blood cultures of 4 deceased individuals, even after storage up to 36 hours without refrigeration.

Conclusions:

  • The study established a baseline HIV-1 prevalence in the investigated fatality cohort in Hamburg.
  • The findings indicate that HIV can remain viable in post-mortem blood for a significant period, even without refrigeration, highlighting potential risks in forensic settings.