Stem cell therapy - Hype or hope? A review.

Area of Science:

• Regenerative Medicine
• Molecular Biology
• Dental Research

Background:

• Tissue regeneration knowledge is ancient, but regenerative medicine/dentistry has advanced recently due to molecular biology.
• Understanding oral tissue regeneration and stem cell research promises a paradigm shift in treating dental diseases.
• Stem cells from orofacial tissues show potential for life-threatening diseases and various dental applications.

Purpose of the Study:

• To review the origin, properties, characteristics, and current research of stem cells.
• To explore the potential applications of stem cells in dentistry.
• To identify challenges in translating stem cell research from laboratory to clinical practice in regenerative dentistry.

Main Methods:

• Literature review of stem cell research in regenerative dentistry.
• Analysis of stem cell isolation from human tissues, including orofacial.
• Examination of current research and potential clinical applications.

Main Results:

• Stem cells have been successfully isolated from various human tissues, including orofacial.
• Pioneering studies indicate stem cells offer breakthroughs for challenging diseases.
• Extensive research explores stem cells' manifold dental applications.

Conclusions:

• Stem cells hold significant promise for regenerative dentistry, offering biological solutions.
• Further research and overcoming clinical translation barriers are crucial for realizing regenerative dentistry's potential.
• The field is advancing towards a new era of regenerative dental applications.