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Updated: Jun 12, 2026

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Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
Keratoconus: overview and update on treatment.
1Department of Ophthalmology, Tulane University, New Orleans, LA, USA.
Middle East African Journal of Ophthalmology
|June 15, 2010
Summary
Keratoconus, a progressive corneal thinning disorder, impacts vision with myopia and astigmatism. Advanced treatments like corneal ring segments, phakic intraocular lenses, and corneal cross-linking offer improved management and visual outcomes.
Area of Science:
- Ophthalmology
- Corneal Diseases
- Refractive Surgery
Background:
- Keratoconus is a non-inflammatory, progressive corneal thinning disorder of unknown cause.
- It frequently results in significant myopia and astigmatism, affecting visual acuity.
- Early diagnosis and management are crucial for preserving vision.
Purpose of the Study:
- To review current diagnostic tools and management strategies for keratoconus.
- To highlight advancements in surgical and non-surgical treatment options.
- To discuss the future outlook for keratoconus management.
Main Methods:
- Review of diagnostic technologies, including computer-assisted corneal topography.
- Analysis of conservative management approaches (spectacles, contact lenses).
- Evaluation of surgical interventions (corneal ring segments, phakic intraocular lenses) and corneal cross-linking.
Main Results:
- Computer-assisted corneal topography aids in diagnosing subclinical keratoconus and monitoring disease progression.
- Intrastromal corneal ring segments and phakic intraocular lenses can correct refractive errors and improve visual acuity.
- Corneal cross-linking effectively stiffens the cornea, halting disease progression.
Conclusions:
- Current management involves a spectrum of options from conservative to surgical interventions.
- Emerging treatments like corneal cross-linking offer new hope for halting keratoconus progression.
- Future management will likely integrate multiple modalities for comprehensive patient care.
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