Related Experiment Video
Updated: Jun 12, 2026

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
Published on: November 10, 2017
The role of statins in managing diabetic dyslipidemia
1Sterling Rock Falls Clinic, Ltd., Sterling, Illinois, USA.
Abstract:
The common lipid abnormalities associated with T2DM confer substantial CV risk. Statins are a safe and well-established treatment option for lowering this atherogenic burden and improving outcomes in this patient population. Nonetheless, many patients with T2DM are not receiving a statin, and even those who receive treatment may not be achieving recommended lipid targets. Strategies must be implemented to improve the quality of care for these patients who are at high risk for a primary or secondary CV event.
Insights
Patients with type 2 diabetes mellitus (T2DM) have high cardiovascular (CV) risk due to lipid issues. Statins can help, but many T2DM patients aren't treated or reaching lipid goals, requiring better care strategies.
Area of Science:
- Cardiology
- Endocrinology
- Pharmacology
Background:
- Type 2 diabetes mellitus (T2DM) is frequently associated with dyslipidemia.
- These lipid abnormalities significantly increase cardiovascular (CV) risk in patients with T2DM.
- Statins are a proven therapy for reducing atherogenic burden and improving CV outcomes.
Purpose of the Study:
- To highlight the unmet need in statin therapy for patients with T2DM.
- To emphasize the importance of achieving lipid targets in this high-risk population.
- To advocate for improved care strategies for T2DM patients at CV risk.
Main Methods:
- Review of current clinical guidelines and evidence regarding lipid management in T2DM.
- Analysis of treatment gaps and challenges in statin utilization and efficacy.
- Discussion of strategies to enhance CV risk reduction in T2DM.
Main Results:
- A significant proportion of patients with T2DM are undertreated with statins.
- Many patients on statin therapy do not achieve recommended lipid targets.
- Suboptimal lipid management contributes to persistent high CV risk.
Conclusions:
- Improved implementation of statin therapy is crucial for T2DM patients.
- Aggressive lipid-lowering strategies are necessary to mitigate CV risk.
- Enhanced quality of care is essential to prevent primary and secondary CV events in this population.
Related Concept Videos
Lipid-Lowering Drugs: Statins and Miscellaneous Agents
Atherosclerosis III: Management
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Angina IV: Management
Coronary Artery Disease IV: Preventive Measures
Atherosclerosis IV: Nursing Management