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Spectroscopic Super-resolution Imaging of DNA Molecules using Intrinsic Contrast
Published on: March 6, 2026
Fluorescence enhancement of single DNA molecules confined in Si/SiO2 nanochannels
Fredrik Westerlund1, Fredrik Persson, Anders Kristensen
1Department of Physics, University of Gothenburg, Gothenburg, Sweden.
Lab on a Chip
|June 15, 2010
Abstract:
We demonstrate that the detected emission intensity from YOYO-labeled DNA molecules confined in 180 nm deep Si/SiO2 nanofunnels changes significantly and not monotonically with the width of the funnel. This effect may be of importance for quantitative fluorescence microscopy and for experiments with a tight photon budget.
