Guidelines for paediatric bone scanning with 99mTc-labelled radiopharmaceuticals and 18F-fluoride

Jan Stauss1, Klaus Hahn, Mike Mann

  • 1Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Insights

These guidelines provide a framework for nuclear medicine teams on pediatric bone scans. They cover indications, acquisition, processing, and interpretation for (99m)Tc-diphosphonate and emerging (18)F-fluoride PET imaging.

Area of Science:

  • Nuclear medicine
  • Pediatric imaging
  • Radiopharmaceuticals

Background:

  • Bone scans are crucial in pediatric diagnostics.
  • Standardized protocols are needed for consistent interpretation.
  • Emerging PET tracers require updated guidance.

Purpose of the Study:

  • To establish guidelines for pediatric bone scintigraphy.
  • To provide a practical framework for nuclear medicine teams.
  • To address both conventional (99m)Tc-diphosphonate and novel (18)F-fluoride PET imaging.

Main Methods:

  • Review of current literature and best practices.
  • Development of recommendations for indications, acquisition, and interpretation.
  • Inclusion of guidelines for (99m)Tc-labelled diphosphonate scintigraphy.
  • Recommendations for positron emission tomography (PET) with (18)F-fluoride.

Main Results:

  • A comprehensive framework for pediatric bone scan procedures.
  • Detailed information on imaging protocols and interpretation criteria.
  • Guidance on the integration of new PET imaging techniques.

Conclusions:

  • These guidelines offer a valuable resource for nuclear medicine professionals.
  • Standardized approaches enhance diagnostic accuracy in pediatric bone imaging.
  • The guidelines support the effective use of both established and novel radiopharmaceuticals.

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