Related Experiment Video
Updated: Jun 12, 2026

Monitoring Equilibrium Changes in RNA Structure by 'Peroxidative' and 'Oxidative' Hydroxyl Radical Footprinting
Published on: October 17, 2011
How to use the computing environment R to analyze ATP-induced ribonucleotide reductase R1 hexamerization data
1Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio 44106, USA. txr24@case.edu
None:
R is an object oriented free and open source statistical computing environment. The R package Combinatorially Complex Equilibrium Model Selection is being developed to meet the analysis challenges of ribonucleotide reductase (RNR). An example of its use is given here. This example involves ATP-induced R1 hexamerization dynamic light scattering data that suggests that R1 hexamers have two types of a-sites, one that binds ATP and another that does not (here, R1 is the large subunit of RNR).

