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Infection caused by Rahnella aquatilis.

Juan I Gaitán1, Michael S Bronze

  • 1Department of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, 73190, USA.

The American Journal of the Medical Sciences
|June 15, 2010
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A rare Rahnella aquatilis bloodstream infection caused septic shock in a sickle cell disease patient with a central venous catheter. Prompt ciprofloxacin treatment led to successful recovery, highlighting the importance of recognizing this pathogen in at-risk individuals.

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Area of Science:

  • Infectious Diseases
  • Microbiology
  • Hematology

Background:

  • Sickle cell disease (SCD) patients are susceptible to infections.
  • Peripherally inserted central venous catheters (PICC) can be a source of bloodstream infections.
  • Rahnella aquatilis is an emerging Gram-negative pathogen rarely associated with human infections.

Purpose of the Study:

  • To report a case of septic shock caused by Rahnella aquatilis in a patient with sickle cell disease.
  • To review the literature on Rahnella aquatilis infections.
  • To discuss the management of Rahnella aquatilis infections in immunocompromised patients.

Main Methods:

  • Case report of a 27-year-old African American woman with SCD and PICC.
  • Identification of Rahnella aquatilis from blood cultures.
  • Literature review of Rahnella aquatilis infections.

Main Results:

  • The patient developed septic shock due to Rahnella aquatilis bacteremia.
  • The infection was successfully treated with ciprofloxacin.
  • Rahnella aquatilis is a rare cause of infection, particularly in immunocompromised individuals.

Conclusions:

  • Rahnella aquatilis can cause severe infections, including septic shock, in patients with underlying conditions like sickle cell disease.
  • Early recognition and appropriate antibiotic therapy (e.g., ciprofloxacin) are crucial for successful outcomes.
  • Further research is needed to understand the pathogenicity and clinical spectrum of Rahnella aquatilis infections.