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A Novel Surgical Technique in a Sheep Model for Suburethral Graft Implantation

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Novel implant for transcervical sterilization.

Muhammad Rehan¹, James Coleman, Abdul Ghani Olabi

¹School of Mechanical and Manufacturing Engineering, Dublin City University, Glasnevin, Dublin 9, Ireland.

Journal of Bioscience and Bioengineering

|June 16, 2010

Summary

A new transcervical implant offers instant, permanent female sterilization without anesthesia or incisions. This novel device uses mechanical occlusion to effectively plug the fallopian tubes, providing a safe and effective alternative for birth control.

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Transvaginal Mesh Insertion in the Ovine Model

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Published on: July 27, 2017

Area of Science:

Biomedical Engineering
Gynecology
Reproductive Health

Background:

Laparoscopic surgery for tubal sterilization requires anesthesia and incisions.
Current transcervical sterilization methods lack instant occlusion.
There is a need for effective, non-surgical female sterilization.

Purpose of the Study:

To design, develop, and test a novel implant for instant permanent female sterilization via the transcervical approach.
To achieve mechanical occlusion of the fallopian tubes using a hysteroscopically deployed device.

Main Methods:

Development of a novel implant with wings for mechanical occlusion.
Three-dimensional (3D) modeling and Finite Element Method (FEM) simulations for implant design.
Validation through bench testing, animal tissue deployment, and explanted human uteri testing.

Main Results:

The implant successfully deployed and achieved instant mechanical occlusion in all tested models.
Hydraulic pressure testing confirmed complete blockage of the fallopian tubes.
FEM simulations informed the design of the implant wings for effective tissue trapping.

Conclusions:

The novel transcervical implant demonstrates potential as a safe and effective method for instant permanent female sterilization.
Further clinical trials are planned to evaluate the device in humans.
This approach offers a promising alternative to surgical sterilization methods.