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Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
Published on: September 22, 2023
Rhinitis is also common in infants with asthma.
Herberto José Chong Neto1, Nelson Augusto Rosário, Gabriele Cardoso Westphal
1Pediatric Allergy Division, Federal University of Paraná Curitiba, Paraná, Brazil. h.chong@uol.com.br
Rhinitis is common in infants with asthma, with similar atopic sensitization rates compared to older children. This highlights the importance of diagnosing allergic rhinitis in young asthmatics.
Area of Science:
- Pediatric Allergy and Immunology
- Respiratory Medicine
Background:
- Asthma and allergic rhinitis frequently coexist in children.
- Early diagnosis and management of comorbidities in pediatric asthma are crucial.
Purpose of the Study:
- To determine the prevalence of rhinitis in infants diagnosed with asthma.
- To compare atopic sensitization rates between asthmatic infants and older asthmatic children with rhinitis.
Main Methods:
- A cross-sectional study analyzed clinical data from asthmatic patients aged 0-14 years.
- Rhinitis diagnosis was based on reported nasal symptoms.
- Allergic sensitization was assessed using skin prick tests for common aeroallergens.
Main Results:
- Rhinitis was diagnosed in 74% of asthmatic infants (under 2 years).
- 36% of these infants showed positive skin prick tests to at least one allergen, with Dermatophagoides pteronyssinus being most common (43%).
- Sensitization rates in infants were similar to older asthmatic children with allergic rhinitis.
Conclusions:
- Rhinitis is highly prevalent in infants with asthma.
- Atopic sensitization patterns in asthmatic infants mirror those in older children with allergic rhinitis.
- Early identification of rhinitis in asthmatic infants is warranted.
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