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Published on: September 22, 2023
Rhinitis is also common in infants with asthma
Herberto José Chong Neto1, Nelson Augusto Rosário, Gabriele Cardoso Westphal
1Pediatric Allergy Division, Federal University of Paraná Curitiba, Paraná, Brazil. h.chong@uol.com.br
Insights
Rhinitis is common in infants with asthma, with similar atopic sensitization rates compared to older children. This highlights the importance of diagnosing allergic rhinitis in young asthmatics.
Area of Science:
- Pediatric Allergy and Immunology
- Respiratory Medicine
Background:
- Asthma and allergic rhinitis frequently coexist in children.
- Early diagnosis and management of comorbidities in pediatric asthma are crucial.
Purpose of the Study:
- To determine the prevalence of rhinitis in infants diagnosed with asthma.
- To compare atopic sensitization rates between asthmatic infants and older asthmatic children with rhinitis.
Main Methods:
- A cross-sectional study analyzed clinical data from asthmatic patients aged 0-14 years.
- Rhinitis diagnosis was based on reported nasal symptoms.
- Allergic sensitization was assessed using skin prick tests for common aeroallergens.
Main Results:
- Rhinitis was diagnosed in 74% of asthmatic infants (under 2 years).
- 36% of these infants showed positive skin prick tests to at least one allergen, with Dermatophagoides pteronyssinus being most common (43%).
- Sensitization rates in infants were similar to older asthmatic children with allergic rhinitis.
Conclusions:
- Rhinitis is highly prevalent in infants with asthma.
- Atopic sensitization patterns in asthmatic infants mirror those in older children with allergic rhinitis.
- Early identification of rhinitis in asthmatic infants is warranted.
Abstract:
The aim of this study was to assess the frequency of rhinitis in asthmatic infants. A cross-sectional study was conducted using clinical data obtained from a standardized allergy work-up form that includes specific questions on common allergic diseases. Asthmatic patients were seen at the first visit to the Pediatric Allergy Unit, from January 2001 to January 2006, were selected for analysis. Diagnosis of allergic rhinitis was based on the presence of two or more nasal symptoms (sneezing, itching, congestion and rhinorrhea). Allergic sensitization was assessed by skin prick test for Dermatophagoides pteronyssinus, Blomia tropicalis, Blattella germanica, Lolium perenne, dog and cat danders. Four hundred and ninety-three infants (under 2 years of age) were selected from a total of 1543 asthmatics aged 0-14 years, 58% males. Physician diagnosis of rhinitis in infants was registered in 367 (74%) and 131 (36%) had positive skin prick test to at least one allergen. Infants were more frequently sensitized to Dermatophagoides pteronyssinus (43%) and Blomia tropicalis (27%). Among asthmatic children > or =2 years old, 890 (84%) also had rhinitis, 773 (87%) were atopic. Among those children with rhinitis, one hundred and eighty six were fully skin prick tested with a standard panel of common aeroallergens. There was no difference between sensitization in asthmatic infants and older asthmatic children with allergic rhinitis. Thus the frequency of rhinitis in asthmatic infants as well as atopic sensitization were similar to older children.
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