Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Aortic valvuloplasty.

R D Safian1, R E Kuntz, A D Berman

  • 1Harvard Medical School, Boston, Massachusetts.

Cardiology Clinics
|May 1, 1991
PubMed
Summary
This summary is machine-generated.

Balloon aortic valvuloplasty (BAV) offers immediate symptom relief for aortic stenosis patients unsuitable for aortic valve replacement (AVR). However, restenosis significantly limits its long-term effectiveness, necessitating careful patient selection.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A checklist of parasites and commensals reported for the chimpanzee (Pan).

Primates; journal of primatology·2016
Same author

Erratum.

Primates; journal of primatology·2016
Same author

Use of purified antigen for detection of Paragonimus westermani and Clonorchis sinensis in peoples of Hsinchu Hsien, Taiwan (Formosa).

Report (U.S. Naval Medical Research Laboratory)·2014
Same author

EPIDEMIOLOGY OF HELMINTH DISEASES: CLONORCHIS SINENSIS (COBBOLD, 1875) LOOSS, 1907 ON TAIWAN (FORMOSA). RES REP MR005.09-1601.3.25.

Report (U.S. Naval Medical Research Laboratory)·2014
Same author

Limitations of cineangiography Impact of new technologies for image processing and quantitation.

Trends in cardiovascular medicine·2011
Same author

Effect of light and temperature on emergence of Schistosoma mansoni cercariae.

Transactions of the American Microscopical Society·2010

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Valvular Heart Disease

Background:

  • Balloon aortic valvuloplasty (BAV) is a palliative procedure for severe aortic stenosis in patients ineligible for aortic valve replacement (AVR).
  • BAV employs various balloon techniques and approaches (retrograde or antegrade) to improve aortic valve function.

Purpose of the Study:

  • To review the mechanisms, outcomes, and limitations of balloon aortic valvuloplasty (BAV).
  • To define the specific clinical scenarios where BAV may be beneficial despite its limitations.

Main Methods:

  • Review of BAV techniques including single, multiple, and complex balloon configurations.
  • Analysis of retrograde (femoral, brachial) and antegrade (transseptal) procedural approaches.
  • Evaluation of hemodynamic changes and clinical outcomes post-BAV.

Related Experiment Videos

Main Results:

  • BAV increases aortic valve area by 50-70% and decreases transaortic valve gradient, improving symptoms.
  • Mechanisms include calcified nodule fracture, commissure separation, and leaflet stretching.
  • The primary limitation is a high restenosis rate, with ~80% experiencing recurrent symptoms within 2 years.

Conclusions:

  • BAV provides significant, albeit temporary, hemodynamic improvement for select aortic stenosis patients.
  • High restenosis rates after BAV suggest that age alone should not preclude AVR consideration.
  • BAV has specific roles in managing patients with contraindications to AVR, urgent non-cardiac surgery, or complex cardiac conditions.