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Related Experiment Video

Updated: Jun 12, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Squamous cell carcinoma masquerading as rhinophyma.

Min Joo Kim¹, Hye Sung Kim, Young Min Park

¹Department of Dermatology, Kangnam St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Annals of Dermatology

|June 16, 2010

Summary

Rhinophyma can hide skin cancers like squamous cell carcinoma (SCC). This case highlights an SCC mimicking rhinophyma, emphasizing the need for careful diagnosis and treatment.

Keywords:

Rhinophyma Squamous cell carcinoma

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Area of Science:

Dermatology
Oncology
Pathology

Background:

Rhinophyma, a benign nasal condition, can obscure underlying skin cancers.
Cutaneous squamous cell carcinoma (SCC) can present with varied morphologies, sometimes mimicking benign lesions.
Coexistence of rhinophyma and SCC is rare, with limited case reports.

Observation:

A 45-year-old man presented with a painful, erythematous, globular nasal lesion resembling rhinophyma.
The lesion's appearance masked a potentially serious underlying condition.
Prompt diagnostic evaluation was initiated due to the lesion's characteristics.

Findings:

Histopathological examination confirmed the presence of cutaneous squamous cell carcinoma (SCC).
Atypical squamous cell proliferation extending into the dermis was identified.
The diagnosis of SCC was established despite the initial rhinophyma-like presentation.

Implications:

This case underscores the importance of thorough histopathological examination for nasal lesions, even those appearing benign.
Dermatologists and oncologists must consider occult malignancies in the differential diagnosis of rhinophyma-like lesions.
Early detection and surgical excision of SCC are crucial for favorable patient outcomes, as demonstrated by the 1-year recurrence-free follow-up.