Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Exercise and Cardiac Output

Exercise and Cardiac Output

Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be met...

Factors Influencing Heart Rate

Factors Influencing Heart Rate

The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...

Exercise and Cardiovascular Response

Exercise and Cardiovascular Response

Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...

Regulation of Heart Rates

Regulation of Heart Rates

The regulation of heart rate is a complex process controlled by the autonomic nervous system (ANS), hormonal influences, and intrinsic cardiac mechanisms. The ANS has two main components: the sympathetic nervous system (SNS) and the parasympathetic nervous system (PNS).
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...

Exercise Stress Test

Exercise Stress Test

Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes

Cardiac Output I:Effect of Heart Rate on Cardiac Output

Cardiac Output I:Effect of Heart Rate on Cardiac Output

Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart rate...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

From Rapid Reviews to Rapid Living Evidence Synthesis: Lessons From COVID-19 Vaccine Effectiveness Reviews for Canadian Public Health Decision-Making.

Campbell systematic reviews·2026

Same author

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2026

Same author

A Qualitative Investigation of Barriers, Facilitators, and Preferences Regarding a Cardiac Rehabilitation-Based Behavioral Weight Loss Program in Adults with Atrial Fibrillation and Obesity.

Behavioral medicine (Washington, D.C.)·2026

Same author

Management of brain-heart multimorbidity: a clinical practice guideline.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2026

Same author

Longitudinal predictors of attachment disorganization: Sociodemographic risk and maternal disrupted caregiving.

Development and psychopathology·2026

Same author

Correction: Canadian healthcare workers' mental health and health behaviours during the COVID-19 pandemic: results from nine representative samples between April 2020 and February 2022.

Canadian journal of public health = Revue canadienne de sante publique·2026

Same journal

Neighborhood-Level Material Resources and Risk of Cardiovascular Events in Patients with Atherosclerotic Cardiovascular Disease.

The Canadian journal of cardiology·2026

Same journal

Storm Clouds Coming: Red-Flag Warning for Hypertension Prevalence and Control in the Post-COVID-19 Era.

The Canadian journal of cardiology·2026

Same journal

Universal coverage, unequal care: Why Canada needs a national cardiovascular access ledger.

The Canadian journal of cardiology·2026

Same journal

Prolonged Loop Recorder Retention: Safety, Diagnostic Yield, and the Case for Community-Based Explantation.

The Canadian journal of cardiology·2026

Same journal

Multimodality Fusion Imaging of Subclinical Systemic Right Ventricular Remodeling in Congenitally Corrected Transposition of the Great Arteries.

The Canadian journal of cardiology·2026

Same journal

Percutaneous Coronary Intervention Prior to Transcatheter Aortic Valve Implantation: A Bayesian Meta-Analysis of Randomized Controlled Trials.

The Canadian journal of cardiology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 12, 2026

Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions

Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions

Published on: June 5, 2019

Improvements in heart rate variability with exercise therapy.

Faye S Routledge¹, Tavis S Campbell, Judith A McFetridge-Durdle

¹Dalhousie University, School of Nursing, Halifax, Nova Scotia, Canada. faye.routledge@duke.edu

The Canadian Journal of Cardiology

|June 16, 2010

Summary

This summary is machine-generated.

Heart rate variability (HRV), a measure of autonomic nervous system function, is often reduced in cardiovascular disease. Exercise therapy may improve HRV, potentially enhancing patient prognosis.

More Related Videos

Real-Time Electrocardiogram Monitoring During Treadmill Training in Mice

Real-Time Electrocardiogram Monitoring During Treadmill Training in Mice

Published on: May 5, 2022

Related Experiment Videos

Last Updated: Jun 12, 2026

Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions

Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions

Published on: June 5, 2019

Real-Time Electrocardiogram Monitoring During Treadmill Training in Mice

Real-Time Electrocardiogram Monitoring During Treadmill Training in Mice

Published on: May 5, 2022

Area of Science:

Cardiology
Autonomic Nervous System Research
Exercise Physiology

Background:

Heart rate variability (HRV) is a key indicator of autonomic nervous system (ANS) function.
Reduced HRV is linked to adverse cardiovascular health and poorer outcomes.
HRV's prognostic value is increasingly recognized across various clinical conditions.

Purpose of the Study:

To review the prognostic implications of HRV in clinical populations.
To examine the effects of interventions, specifically exercise therapy, on HRV.
To explore the potential mechanisms by which exercise impacts HRV.

Main Methods:

Systematic review of existing research on HRV and cardiovascular health.
Analysis of studies investigating interventions aimed at improving HRV.
Examination of physiological mechanisms potentially mediating exercise-induced HRV changes.

Main Results:

Reduced HRV is a significant prognostic marker in myocardial infarction, heart failure, unstable angina, and diabetes.
Exercise therapy demonstrates potential to improve HRV in patients post-myocardial infarction, with chronic heart failure, and after revascularization.
Exercise appears to enhance HRV by increasing vagal tone and reducing sympathetic activity.

Conclusions:

Exercise therapy may be a beneficial intervention for improving HRV in cardiovascular patients.
Increased vagal modulation, potentially induced by exercise, could positively influence patient prognosis.
Angiotensin II and nitric oxide are hypothesized as mediators in exercise-induced improvements in vagal modulation.