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Related Experiment Videos

Principles of measles control.

F T Cutts1, R H Henderson, C J Clements

  • 1Immunization Division, Centers for Disease Control, Atlanta, GA 30333.

Bulletin of the World Health Organization
|January 1, 1991
PubMed
Summary
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Measles outbreaks can occur even with high vaccination rates. Achieving near-perfect immunization coverage and strategic vaccination of susceptible populations are crucial for measles control and prevention.

Area of Science:

  • Public Health
  • Epidemiology
  • Immunology

Background:

  • The Expanded Programme on Immunization has reduced global measles morbidity and mortality.
  • Recent measles outbreaks in African countries with high vaccine coverage highlight challenges in achieving herd immunity.
  • Sustained measles control requires addressing susceptible populations and optimizing vaccination strategies.

Purpose of the Study:

  • To analyze the epidemiology of measles outbreaks in areas with high vaccine coverage.
  • To identify strategies for improving measles control and prevention programs.
  • To inform public health interventions for reducing measles incidence.

Main Methods:

  • Review of measles epidemiology data in African countries.
  • Analysis of vaccine coverage levels and outbreak patterns.

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  • Assessment of current immunization target age groups and strategies.

    • Main Results:

    • Measles outbreaks can occur in populations with high vaccination coverage, particularly in children outside the target age group.
    • Achieving near 100% immunization coverage with highly effective vaccines is essential for complete measles elimination.
    • Targeting urban and densely populated rural areas, and vaccinating infants at 6 months with high-dose vaccines can improve coverage.

    Conclusions:

    • Effective measles control necessitates identifying and reaching susceptible populations, especially in urban settings.
    • Adjusting immunization strategies, including vaccinating older children when appropriate and improving data collection, is vital.
    • Enhanced surveillance and data utilization are critical for monitoring program impact and responding to outbreaks.