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Related Concept Videos

Nurses' Legal Responsibilities I01:27

Nurses' Legal Responsibilities I

In healthcare, informed consent is a crucial process that involves thoroughly communicating medical treatment options to patients, including benefits, risks, potential side effects, and alternatives. This process enables patients to make well-informed decisions about their care, ensuring they understand the implications of their choices before consenting to or refusing treatment.
The legal responsibilities of a nurse regarding informed consent include the following:
Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment01:08

Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment

Hepatic impairment, characterized by decreased liver function, does not uniformly mandate adjustments in drug dosage. Whether dosage modifications are necessary depends on various factors related to the drug's metabolism and elimination pathways. If a drug is primarily excreted via the kidneys and bypasses significant hepatic processing, if it undergoes minimal metabolic transformation in the liver, or if it is volatile and primarily expelled through the lungs, dose adjustments may not be...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Obedience01:08

Obedience

According to obedience research, we may harm others under the forceful pressures of an authority figure (Milgram, 1974). How about if the inappropriate orders were delivered with less force? The increasing interdependence between nurses and physicians compelled Hofling and his colleagues to explore nurses’ reactions to a potentially harmful medical request made by the perceived authority figure, the doctor (Hofling, Brotzman, Dalrymple, Graves, & Pierce, 1966). In this situation, obedience...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Psychosurgery01:30

Psychosurgery

Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...

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Related Experiment Video

Updated: Jun 12, 2026

A Familiarization Protocol Facilitates the Participation of Children with ASD in Electrophysiological Research
08:42

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Published on: July 31, 2017

Consent in impaired populations.

Paul S Appelbaum1

  • 1New York State Psychiatric Institute, Unit #122, 1051 Riverside Drive, New York, NY 10032, USA. psa21@columbia.edu

Current Neurology and Neuroscience Reports
|June 16, 2010
PubMed
Summary

Patients with cognitive impairments, including dementia, may have reduced capacity for informed consent. Structured evaluations and legal options like advance directives can help ensure patient rights are respected.

Area of Science:

  • Neuroscience
  • Medical Ethics
  • Cognitive Psychology

Background:

  • Cognitive impairments, such as those seen in dementia, can affect a patient's ability to provide informed consent for medical treatment or research participation.
  • Mild cognitive impairment and early-stage dementia often lead to decrements in decisional abilities.

Purpose of the Study:

  • To review the impact of cognitive impairments on decisional capacity.
  • To discuss methods for evaluating and supporting patient consent.
  • To outline legal frameworks for substitute consent when capacity is lacking.

Main Methods:

  • Literature review on cognitive impairment and decisional capacity.
  • Discussion of clinical evaluation tools for competence.
  • Analysis of legal provisions for substitute consent.

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Last Updated: Jun 12, 2026

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Published on: July 31, 2017

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Main Results:

  • Most patients with mild dementia likely retain competence for consent, and some with moderate dementia may in specific situations.
  • Structured clinical evaluations and instruments can reliably assess decisional competence.
  • Legal options such as advance directives and familial consent serve as substitute consent mechanisms.

Conclusions:

  • Cognitive impairments necessitate careful evaluation of decisional capacity.
  • Evaluations should be designed to maximize patient performance to uphold autonomy.
  • When substitute consent is required, legal frameworks provide established options.