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Magnesium, calcium, and trace elements excretion in 24-h urine
Maria Długaszek1, Mirosława Kaszczuk, Monika Mularczyk-Oliwa
1Military University of Technology, Institute of Optoelectronics, Warsaw, Poland. mdlugaszek@wat.edu.pl
Biological Trace Element Research
|June 16, 2010
Summary
This study analyzed essential and toxic elements in 24-hour urine samples from 74 adults. Results show gender and age influence zinc, calcium, and lead excretion, impacting elemental status.
Area of Science:
- Clinical Chemistry
- Environmental Health
- Analytical Chemistry
Background:
- Urine analysis is crucial for medical diagnostics, monitoring element concentrations and kidney function.
- Understanding elemental excretion patterns is vital for assessing health and environmental exposure.
- Previous studies have explored specific elements, but comprehensive analysis considering demographics is needed.
Purpose of the Study:
- To quantify magnesium, calcium, zinc, copper, iron, lead, and cadmium in 24-hour urine samples.
- To investigate the influence of sex and age on the excretion of these elements.
- To explore correlations between different elements and their relationship with age.
Main Methods:
- Atomic absorption spectrometry (AAS) with flame (FAAS) and graphite furnace (GFAAS) atomization.
- Analysis of 74 samples of 24-hour urine from 46 women and 28 men.
- Statistical analysis including sex, age, element correlations, and age-element relationships.
Main Results:
- Significant differences in zinc excretion between men and women were observed.
- Adults (>18 years) showed higher calcium excretion compared to younger subjects.
- A significant positive correlation was found between lead levels and age across all donors.
Conclusions:
- Gender and age are significant factors influencing elemental status in 24-hour urine.
- Specific elemental correlations (e.g., Ca-Mg, Pb-Cd) suggest interconnected metabolic or exposure pathways.
- These findings contribute to a better understanding of human elemental homeostasis and potential health implications.
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