Related Experiment Video
Updated: Jun 12, 2026

Automated Hydrophobic Interaction Chromatography Column Selection for Use in Protein Purification
Published on: September 21, 2011
[Recent advances in column for hydrophilic interaction capillary electrochromatography]
Xucong Lin1, Jia Lin, Jiabin Wang
1Institute of Food Safety and Environmental Monitoring, Fuzhou University, Fuzhou 350108, China.
Hydrophilic interaction capillary electrochromatography (HI-CEC) research is advancing, focusing on stationary phase development. This review covers open-tubular, particle-packed, and monolithic columns, highlighting recent monolithic CEC progress.
Area of Science:
- Analytical Chemistry
- Separation Science
- Chromatography
Context:
- Hydrophilic interaction capillary electrochromatography (HI-CEC) is a key micro-separation technique.
- Development of effective stationary phases is crucial for HI-CEC performance.
Purpose:
- To review the research progress of stationary phase materials for HI-CEC.
- To highlight recent advancements in monolithic columns for HI-CEC.
Summary:
- This paper reviews HI-CEC stationary phase research, including open-tubular, particle-packed, and monolithic columns.
- Special attention is given to recent developments in monolithic column technology for HI-CEC.
Impact:
- Provides a comprehensive overview of HI-CEC stationary phase evolution.
- Identifies key trends and future directions in monolithic HI-CEC column development.
Related Concept Videos
Ion-Exchange Chromatography
Principles Of Column Chromatography
Capillary Electrophoresis: Applications
Capillary zone electrophoresis (CZE) separates ionic components based on their electrophoretic mobility. It has been used to separate proteins, amino acids,...
High-Performance Liquid Chromatography: Introduction
In HPLC, two phases play a critical role in the separation process:
High-Performance Liquid Chromatography: Elution Process
Types Of Column Chromatography
Gel Filtration Chromatography
When the...
