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Related Concept Videos

The Oral Microbiota01:27

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...

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Related Experiment Video

Updated: Jun 12, 2026

2-Methacryloyloxyethyl Phosphorylcholine Polymer Treatment of Complete Dentures to Inhibit Denture Plaque Deposition
06:02

2-Methacryloyloxyethyl Phosphorylcholine Polymer Treatment of Complete Dentures to Inhibit Denture Plaque Deposition

Published on: December 26, 2016

Temporal changes of denture plaque microbiologic composition evaluated in situ.

Tatiana Pereira-Cenci1, Wander José da Silva, Maximiliano Sérgio Cenci

  • 1Department of Restorative Dentistry, School of Dentistry, Universidade Federal del Pelotas, Brazil. altcury@fop.unicamp.br

The International Journal of Prosthodontics
|June 17, 2010
PubMed
Summary

Biofilm composition on dentures changes over time, with increased Candida glabrata and other microbes after 7 and 14 days. Denture material did not significantly impact biofilm development in this study.

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Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
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Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Published on: December 31, 2017

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Last Updated: Jun 12, 2026

2-Methacryloyloxyethyl Phosphorylcholine Polymer Treatment of Complete Dentures to Inhibit Denture Plaque Deposition
06:02

2-Methacryloyloxyethyl Phosphorylcholine Polymer Treatment of Complete Dentures to Inhibit Denture Plaque Deposition

Published on: December 26, 2016

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
10:42

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Published on: December 31, 2017

Area of Science:

  • Oral Microbiology
  • Biomaterials Science
  • Dental Prosthetics

Background:

  • Denture biofilm harbors microorganisms, potentially leading to oral health issues.
  • Understanding biofilm dynamics is crucial for denture hygiene and patient well-being.

Purpose of the Study:

  • To investigate the impact of time and denture material on oral biofilm composition.
  • To quantify microbial changes in biofilm over a 14-day period.

Main Methods:

  • Biofilm was cultivated on acrylic resin and denture liner specimens for 14 days in complete denture wearers.
  • Specimens were collected on days 2, 7, and 14 for microbial analysis.
  • Quantitative analysis focused on Candida glabrata, total streptococci, Actinomyces, and total microorganisms.

Main Results:

  • Microbial counts, including Candida glabrata, total streptococci, Actinomyces, and total microorganisms, significantly increased after 7 and 14 days (P < .05).
  • Candida glabrata exhibited a progressive increase in counts from day 2 to day 14.
  • No significant differences in biofilm composition were observed between acrylic resin and denture liner materials.

Conclusions:

  • Denture biofilm composition is significantly influenced by the duration of biofilm formation.
  • Candida glabrata is a key species that accumulates progressively over time on dentures.
  • Denture material type does not appear to be a major factor in early-stage biofilm composition.