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Updated: Jun 12, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Successful congenital heart surgery for a toddler with idiopathic infantile arterial calcification
Margaret M Samyn1, David Bick, John A Humphrey
1Herma Heart Center, Children's Hospital of Wisconsin, Milwaukee, WI, 53226, USA. msamyn@chw.org
Insights
Idiopathic infantile arterial calcification (IIAC) is often fatal in infants. This case report details successful cardiac surgery in a 27-month-old boy with IIAC, overcoming severe pulmonary valve stenosis.
Area of Science:
- Pediatric Cardiology
- Cardiovascular Surgery
- Rare Genetic Diseases
Background:
- Idiopathic infantile arterial calcification (IIAC) is a rare genetic disorder characterized by diffuse calcification of large arteries.
- IIAC typically presents in early infancy with a high mortality rate, often within the first six months of life.
- Severe cardiovascular complications, such as valvular stenosis, can arise in affected infants.
Abstract:
We present the first case report of successful cardiac surgery in a child with idiopathic infantile arterial calcification (IIAC), a disease that is generally lethal within the first 6 months of life. This 27-month-old Hispanic American boy with IIAC successfully underwent cardiothoracic surgery for severe pulmonary valve (PV) stenosis after unsuccessful balloon valvotomy in the cardiac catheterization laboratory.
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