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Updated: Jun 12, 2026

Laparoscopic Left Lateral Sectionectomy: Guided by the Ligamentum Teres Hepatis and the Umbilical Fissure Vein

Laparoscopic Left Lateral Sectionectomy: Guided by the Ligamentum Teres Hepatis and the Umbilical Fissure Vein

Published on: September 27, 2024

Peritoneal changes due to laparoscopic surgery.

W J A Brokelman¹, M Lensvelt, I H M Borel Rinkes

¹Department of Surgery, Jeroen Bosch Hospital, P.O. Box 1101, 5200 BD, 's-Hertogenbosch, The Netherlands. w.brokelman@jbz.nl

Surgical Endoscopy

|June 17, 2010

Summary

This summary is machine-generated.

Laparoscopic surgery impacts peritoneal integrity and biology, similar to open surgery. These changes, including acidosis and immune modulation, may affect clinical outcomes like metastasis and adhesion formation.

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Area of Science:

Surgical Science
Peritoneal Biology

Background:

Laparoscopic surgery is common practice.
The peritoneum has diverse biological functions potentially altered by surgical techniques.
Peritoneal changes are clinically relevant for metastasis and adhesion formation.

Purpose of the Study:

To investigate the effects of laparoscopic surgery on peritoneal integrity and biology.
To compare laparoscopic and open surgery impacts on the peritoneum.
To explore clinical implications of peritoneal alterations.

Main Methods:

Literature search of Pubmed and Cochrane databases.
Focused on laparoscopy, peritoneum, inflammation, morphology, immunology, and fibrinolysis.

Main Results:

Laparoscopic surgery alters peritoneal integrity, causing local acidosis possibly due to hypoxia.
Pneumoperitoneum modulates the local immune system and inflammation.
Peritoneal hypofibrinolysis occurs due to inhibition of the peritoneal plasmin system.

Conclusions:

Laparoscopic surgery affects peritoneal integrity and biology, akin to open surgery.
These peritoneal alterations may have significant clinical implications.