Related Experiment Video
Updated: Jun 12, 2026

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Coronary artery calcium scoring in cardiovascular risk assessment
Gaetano Nucifora1, Jeroen J Bax, Jacob M van Werkhoven
1Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, Leiden, the Netherlands. gnucifora@cardionet.it
Insights
Coronary artery disease (CAD) risk can be better assessed using coronary artery calcium scoring (CACS) alongside traditional methods. This imaging technique improves patient risk stratification for future cardiac events.
Area of Science:
- Cardiology
- Radiology
- Preventive Medicine
Background:
- Traditional risk scores (e.g., Framingham, Heart Score) identify coronary artery disease (CAD) risk but may miss some patients.
- Subclinical atherosclerosis visualization is proposed to enhance risk stratification.
- Coronary calcium is a direct marker of atherosclerosis.
Purpose of the Study:
- To review the literature on the prognostic value of coronary artery calcium scoring (CACS).
- To discuss other potential applications and limitations of CACS assessment.
Main Methods:
- Review of existing literature on CACS assessment.
- Utilizing electron-beam and multislice computed tomography for CACS estimation.
Main Results:
- CACS assessment provides incremental prognostic information beyond traditional risk scores.
- Noninvasive assessment of CACS using computed tomography is supported by substantial data.
- CACS aids in identifying patients with subclinical atherosclerosis at risk for future CAD events.
Conclusions:
- CACS assessment offers valuable prognostic information for cardiovascular risk stratification.
- The technique has potential applications beyond risk prediction.
- Understanding the limitations of CACS is crucial for its effective clinical use.
Abstract:
Identification of patients at risk of future coronary artery disease (CAD) events traditionally relies on scoring tools that take demographic and clinical characteristics into account (e.g., the Framingham risk score in the United States and the Heart Score in Europe). Although these scoring tools have been shown to have a good predictive value, they may still fail to recognize a proportion of patients with coronary atherosclerosis at risk for future CAD events. In order to improve risk stratification, direct visualization of subclinical atherosclerosis has been advocated. Electron-beam computed tomography and multislice computed tomography provide a direct estimation of coronary calcium, a marker of coronary atherosclerosis. A large amount of data is available supporting the clinical value of the noninvasive assessment of coronary artery calcium score (CACS) with these techniques and its incremental prognostic information over traditional risk stratification. Aim of this review is to provide an overview of the literature regarding the prognostic value of CACS assessment. In addition, potential other applications of CACS assessment as well as the limitations of the technique are discussed.
More Related Videos
06:57Semi-Automatic Graphical Tool for Measuring Coronary Artery Spatially Weighted Calcium Score from Gated Cardiac Computed Tomography Images
Published on: September 22, 2023
06:16Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
Published on: August 9, 2024
Related Concept Videos
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Imaging Studies for Cardiovascular System V: CT
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Acute Coronary Syndrome III: Diagnostic Studies
Coronary Artery Disease IV: Preventive Measures
Coronary Artery Disease I: Introduction