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Related Experiment Video

Updated: Jun 12, 2026

Probiotic Studies in Neonatal Mice Using Gavage
10:36

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Published on: January 27, 2019

Nutraceuticals in the early infancy.

Pasquale Pignatelli1, Stefania Basili

  • 1Divisione I Clinica Medica Università Sapienza, Roma, Italy. Pasquale.pignatelli@uniroma1.it

Cardiovascular Therapeutics
|June 18, 2010
PubMed
Summary
This summary is machine-generated.

Nutritional strategies and nutraceuticals may help reduce childhood atherosclerosis risk factors like obesity and high cholesterol. However, current evidence is weak, so these should not be used clinically in children yet.

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Area of Science:

  • Pediatrics
  • Cardiovascular Health
  • Nutritional Science

Background:

  • Childhood atherosclerosis risk factors, including obesity, hypercholesterolemia, diabetes mellitus, and hypertension, are increasingly recognized.
  • Early atherosclerosis development in children is linked to these established risk factors.
  • Dietary interventions show promise in managing these risk factors during childhood.

Purpose of the Study:

  • To review current nutritional and nutraceutical strategies for modifying childhood atherosclerosis risk factors.
  • To evaluate the evidence for specific nutrients like fiber, omega-3 fatty acids, vitamin D, antioxidants, and calcium.
  • To assess the potential role of nutraceuticals in preventing cardiovascular complications in children.

Main Methods:

  • Systematic review of existing literature on nutritional and nutraceutical interventions.
  • Analysis of studies focusing on specific nutrients and their impact on cardiovascular risk factors in children.
  • Evaluation of the safety and efficacy data from analyzed studies.

Main Results:

  • Some nutraceuticals show potential for reducing atherosclerosis risk factors in children.
  • Nutrients such as fiber, omega-3 fatty acids, vitamin D, antioxidants, and calcium were specifically examined.
  • Evidence suggests certain dietary approaches may influence childhood cardiovascular health.

Conclusions:

  • While some nutraceuticals appear promising, current research has methodological limitations.
  • Nutrients and supplements are not yet recommended as clinical therapies for children at risk of cardiovascular disease.
  • Further high-quality research is needed to establish the clinical utility of these interventions.