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Updated: Jun 12, 2026

Preparation of Multifunctional Silk-Based Microcapsules Loaded with DNA Plasmids Encoding RNA Aptamers and Riboswitches

Preparation of Multifunctional Silk-Based Microcapsules Loaded with DNA Plasmids Encoding RNA Aptamers and Riboswitches

Published on: October 8, 2021

Recent progress in bio-sensing techniques with encapsulated enzymes.

Byung-Wook Park¹, Do-Young Yoon, Dong-Shik Kim

¹Department of Chemical & Environmental Engineering, University of Toledo, Toledo, OH 43606, USA.

Biosensors & Bioelectronics

|June 18, 2010

Summary

This summary is machine-generated.

Encapsulated enzyme biosensors offer improved selectivity and activity. This review covers recent advancements in liposome, polymer, sol-gel, hydro-gel, and peptide encapsulation techniques for biosensor development.

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Preparation of Multifunctional Silk-Based Microcapsules Loaded with DNA Plasmids Encoding RNA Aptamers and Riboswitches

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Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Published on: February 16, 2018

Area of Science:

Biotechnology
Analytical Chemistry
Materials Science

Background:

Biosensors utilize encapsulated enzymes for enhanced substrate selectivity and sustained activity.
Enzyme encapsulation in materials like liposomes, polymers, sol-gels, and hydro-gels is crucial for biosensor performance.
Maintaining enzyme activity and selectivity through novel encapsulation methods is an ongoing research focus.

Purpose of the Study:

To review recent progress in encapsulated enzyme biosensors over the last decade.
To categorize and analyze advancements based on encapsulation techniques.
To identify future research directions in the field.

Main Methods:

Systematic review of peer-reviewed literature on encapsulated enzyme biosensors published in the last 10 years.
Categorization of reviewed articles based on four main encapsulation methods: liposome, polymer, sol-gel/hydro-gel, and peptide.
Comparative analysis of critical and noticeable research articles within each category.

Main Results:

Recent advancements focus on novel materials and encapsulation techniques to improve enzyme stability and biosensor performance.
Mass transfer limitations remain a key challenge in encapsulated enzyme biosensor design.
Diverse encapsulation strategies offer tailored solutions for specific sensing applications.

Conclusions:

Encapsulated enzyme biosensors show significant promise for various applications due to improved enzyme characteristics.
Further research into advanced materials and techniques is needed to overcome limitations like mass transfer.
Future directions include exploring new encapsulation methods and optimizing existing ones for enhanced biosensing capabilities.