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A clinical study of hospitalized H1N1 infected children in Western Rajasthan

B D Gupta1, Adarsh Purohit

  • 1Department of Pediatrics, Umaid Hospital for Women and Children, Regional Institute for Maternal & Child Health, Dr S. N. Medical College, Jodhpur, Rajasthan, India. dradarshpurohit@gmail.com

Journal of Tropical Pediatrics
|June 18, 2010
PubMed

Insights

Pandemic 2009 H1N1 influenza caused severe respiratory issues in hospitalized children. This strain led to complications like consolidation, pleural effusion, and pneumothorax, unlike typical seasonal flu.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Respiratory Medicine

Background:

  • The 2009 H1N1 influenza pandemic posed a significant global health threat.
  • Understanding the clinical impact of H1N1 influenza in pediatric populations is crucial for public health preparedness.

Purpose of the Study:

  • To investigate the clinical characteristics and outcomes of children hospitalized with 2009 H1N1 influenza.
  • To identify specific respiratory complications associated with H1N1 influenza in pediatric patients.

Main Methods:

  • Retrospective analysis of hospital records for pediatric patients diagnosed with H1N1 influenza.
  • Confirmation of H1N1 influenza by throat swab real-time polymerase chain reaction (rt-PCR).

Main Results:

  • 62 children were hospitalized with 2009 H1N1 influenza between November 2009 and February 2010.
  • 30.6% of admitted children required intensive care unit (ICU) admission, and 6.4% expired.
  • Significant respiratory complications included consolidation (40%), pleural effusion (6%), pneumothorax (1.6%), and pulmonary edema (1.6%).

Conclusions:

  • Pandemic 2009 H1N1 influenza was associated with severe respiratory complications in children.
  • These complications, such as consolidation and pneumothorax, were more severe than those typically observed with seasonal influenza strains.
Abstract

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