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Psychomotor and motor functioning in children with cryptogenic localization related epilepsy
Saskia G M van Mil1, Nora M de la Parra, Rianne P Reijs
1Department of Research and Development, Epilepsy Centre Kempenhaeghe, Heeze, The Netherlands.
Insights
Children with cryptogenic localization related epilepsy (CLRE) often exhibit psychomotor and motor deficits. Slower reaction times and poorer motor skills, like manual dexterity and balance, are common in CLRE patients.
Area of Science:
- Pediatric Neurology
- Neurodevelopmental Disorders
- Motor Control
Background:
- Epilepsy in children can impact cognitive and motor development.
- Cryptogenic localization related epilepsy (CLRE) is a specific epilepsy syndrome requiring further investigation into its functional consequences.
- Understanding psychomotor and motor functioning is crucial for comprehensive care of children with CLRE.
Purpose of the Study:
- To assess psychomotor and motor functioning in children diagnosed with CLRE.
- To identify specific areas of deficit in motor skills and reaction times.
- To explore the relationship between psychomotor and motor performance in this population.
Main Methods:
- Inclusion of eighty-nine children with CLRE.
- Comparison of reaction time measurements and motor functioning tasks against age-related normative data.
- Calculation of correlations between psychomotor and motor task performances.
Main Results:
- Approximately 35% of CLRE children experience manual dexterity and balance issues.
- Around 55% of CLRE children face challenges with ball skills.
- CLRE children demonstrated significantly slower simple reaction times and lower performance on the Movement Assessment Battery for Children (m-ABC) compared to norms.
- A positive correlation was found: better simple reaction time correlated with better m-ABC performance.
Conclusions:
- Children with CLRE frequently present with significant psychomotor and motor impairments.
- Deficits in reaction time, manual dexterity, balance, and ball skills are prevalent in CLRE.
- Improved psychomotor function, specifically reaction time, is associated with better overall motor performance in CLRE.
Abstract:
The aim of this study is to investigate psychomotor- and motor functioning in children with cryptogenic localization related epilepsy (CLRE) and to explore possible relationships between these two functions. Eighty-nine children were included. Results of reaction times measurements and motor functioning tasks were compared to age-related normative values. Correlations between the psychomotor and motor tasks were computed. Manual dexterity and balance problems are present in about 35% of CLRE-children. Ball skills are problematic in approximately 55% of the children. Simple reaction time measurements showed significantly slowing for CLRE children relative to the reference values. Also, performance on the m-ABC was significantly lower than the reference values. The better the child's performance on the simple reaction time measurements, the better the performance on the m-ABC.
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