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Extraction of Structural Extracellular Polymeric Substances from Aerobic Granular Sludge
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Activated sludge behaviour in a batch reactor in the presence of antibiotics: study of extracellular polymeric

A C Avella1, M Essendoubi, J N Louvet

  • 1Laboratoire Environnement et Minéralurgie, Nancy-Université, LEM UMR CNRS INPL 7569, 15 avenue du Charmois, 54500 Vandoeuvre-les-Nancy, France. catalina.avella@ensg.inpl-nancy.fr

Water Science and Technology : a Journal of the International Association on Water Pollution Research
|June 18, 2010
PubMed

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Penicillin, one of the earliest and most widely used antibiotics, is produced industrially by the filamentous fungus Penicillium chrysogenum. Large stirred-tank bioreactors ranging from tens to hundreds of thousands of liters maintain tightly controlled temperature, pH, and dissolved oxygen conditions to support fungal metabolism and maximize antibiotic yield. Penicillin is a secondary metabolite, synthesized primarily during the stationary growth phase, which requires a carefully managed...