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Updated: Jun 12, 2026

Highly Sensitive and Rapid Fluorescence Detection with a Portable FRET Analyzer
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A sensitive and highly selective fluorescent sensor for In(3+).

Yan-Chao Wu1, Hui-Jing Li, Hua-Zheng Yang

  • 1State Key Laboratory of Element-Organic Chemistry, Institute of Element-Organic Chemistry, Nankai University, Tianjin 300071, China. ycwu@iccas.ac.cn

Organic & Biomolecular Chemistry
|June 18, 2010
PubMed
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A new fluorescent sensor selectively detects indium(III) ions. This pyrazolo[1,5-a]pyrimidine-based sensor shows a strong fluorescence response, offering a unique tool for indium(III) detection.

Area of Science:

  • Analytical Chemistry
  • Materials Science

Background:

  • Selective detection of metal ions is crucial in environmental monitoring and diagnostics.
  • Indium(III) ion (In3+) plays a role in various industrial applications and biological processes, necessitating accurate quantification methods.

Purpose of the Study:

  • To develop a simple, neutral fluorescent sensor for selective indium(III) ion detection.
  • To investigate the sensor's response to various metal ions and its performance in acetonitrile.

Main Methods:

  • Synthesis of a pyrazolo[1,5-a]pyrimidine derivative as a fluorescent probe.
  • Spectroscopic analysis (fluorescence spectroscopy) to evaluate the sensor's response to In3+.
  • Testing selectivity against a range of common metal ions in acetonitrile solution.

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An Aptamer-based Sensor for Unchelated Gadolinium(III)
05:15

An Aptamer-based Sensor for Unchelated Gadolinium(III)

Published on: January 9, 2017

Main Results:

  • The pyrazolo[1,5-a]pyrimidine sensor demonstrated high selectivity for indium(III) ions.
  • A dramatic and distinct fluorescence enhancement was observed upon binding with In3+.
  • The sensor showed minimal interference from other tested metal ions, including transition metals and alkali metals.

Conclusions:

  • The developed sensor offers a promising and selective method for detecting indium(III) ions.
  • The unique fluorescence response highlights its potential for practical applications in indium(III) sensing.
  • The sensor's simplicity and selectivity make it a valuable tool in analytical chemistry.