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Related Concept Videos

Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
Epigenetic Regulation01:46

Epigenetic Regulation

Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
Epigenetic Regulation01:37

Epigenetic Regulation

Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
Epigenetic Regulation01:46

Epigenetic Regulation

Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
Inheritance of Chromatin Structures03:17

Inheritance of Chromatin Structures

Epigenetics is the study of inherited changes in a cell's phenotype without changing the DNA sequences. It provides a form of memory for the differential gene expression pattern to maintain cell lineage, position-effect variegation, dosage compensation, and maintenance of chromatin structures such as telomeres and centromeres. For example, the structure and location of the centromere on chromosomes are epigenetically inherited. Its functionality is not dictated or ensured by the underlying DNA...
Gene-Environment Interactions01:20

Gene-Environment Interactions

Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...

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Related Experiment Video

Updated: Jun 12, 2026

Stable Isotope In-Vivo Labeling for Mass-Spectrometry Identification of Paternal Metabolites Transferred from Sperm to Oocyte During Fertilization
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Stable Isotope In-Vivo Labeling for Mass-Spectrometry Identification of Paternal Metabolites Transferred from Sperm to Oocyte During Fertilization

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[Contribution of epigenetics to understand human development].

Paula Bedregal1, Beatriz Shand, Manuel J Santos

  • 1Departamento de Salud Pública, Escuela de Medicina, Pontificia Universidad Católica de Chile. pbedrega@med.puc.cl

Revista Medica De Chile
|June 18, 2010
PubMed
Summary

Epigenetics influences human development and health. Early life events can impact adult health through epigenetic mechanisms, informing future research and public policy.

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Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain
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Area of Science:

  • Explores the field of epigenetics, focusing on gene expression regulation without altering DNA sequence.

Context:

  • Reviews recent epigenetic discoveries relevant to human development.
  • Highlights the connection between epigenetics and perinatal epidemiological issues.

Purpose:

  • To provide a comprehensive overview of epigenetic mechanisms in human development.
  • To analyze the influence of early life events on adult health via epigenetic pathways.

Summary:

  • Discusses epigenetic contributions to physiological and pathological conditions.
  • Examines epidemiological and animal study evidence linking perinatal events to adult outcomes through epigenetics.

Impact:

  • Underscores the implications for future research directions in developmental biology and public health.
  • Emphasizes the need for public policies that consider the long-term impact of early life experiences on individual development.