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The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...

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Related Experiment Video

Updated: Jun 12, 2026

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Published on: December 4, 2020

[Actinomycosis in persistent urachus].

Marcin Bednarek¹, Leszek Bolt, Zbigniew Biesiada

¹II Katedra Chirurgii Collegium Medicum UJ. czerwonachirurgia@wp.pl

Przeglad Lekarski

|June 19, 2010

Summary

This case report details a rare instance of Gram-positive Actinomyces found in a urachal tumor in a 70-year-old woman. This finding highlights an unusual pathogen in a rare tumor location.

Area of Science:

Urology
Pathology
Medical Microbiology

Background:

Urachal tumors are rare malignancies arising from remnants of the allantois.
Actinomycosis is a bacterial infection typically caused by Gram-positive bacteria, often presenting as a chronic granulomatous disease.

Observation:

A 70-year-old female patient presented with a confirmed urachal tumor, diagnosed via ultrasound (USG) and computed tomography (CT).
Histopathological examination of the tumor revealed the presence of Gram-positive Actinomyces.

Findings:

The definitive histopathology confirmed Actinomyces as an incidental finding within the urachal tumor.
The co-occurrence of Actinomyces within a urachal tumor represents a highly uncommon presentation.

Implications:

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This case underscores the importance of thorough histopathological evaluation for identifying unexpected pathogens in rare tumor types.
The findings may contribute to understanding the potential for microbial involvement in urachal pathologies.
Further research could explore the pathogenesis and clinical significance of Actinomyces in urachal remnants.