Related Experiment Video
Updated: Jun 12, 2026

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
Published on: July 3, 2013
[Contrast-induced nephropathy]
Insights
Contrast-induced nephropathy (CIN) is a kidney injury complication following contrast procedures. Research continues on effective prevention and treatment strategies for this serious condition.
Area of Science:
- Nephrology
- Cardiology
- Radiology
Abstract:
Contrast-induced nephropathy is a major complication resulting from percutaneous coronary interventional procedures characterized by acute or subacute deterioration of renal function due to exposure to iodinated contrast medium that is associated with increased morbidity and mortality. Promoting factors for the development of nephropathy have been widely described in literature as well as hydration and pharmacological measures to prevent its development; However, few of them have shown evidence level A so far, hence a major research front remains open, not only in the prevention but also in the treatment of this pathology. In this article we review epidemiological and pathophysiological aspects of this complication, and various preventive and therapeutic modalities currently available.
Related Concept Videos
Chronic Kidney Disease II: Clinical Manifestations
Diabetic Nephropathy
Acute Kidney Injury II: Pathophysiology
Acute Kidney Injury III: Clinical Manifestations
Acute Kidney Injury I: Introduction
Chronic Kidney Disease I: Introduction